Forbidden Fitness Secrets Of A Modern Day Ninja Warrior
Forbidden Fitness Secrets is used by legendary Japanese Shadow Warriors to reinforce Joints, Ligaments And Tendons to an almost Supernatural Breaking Point.
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After Bruno Fernandes’ last-gasp penalty winner against Brighton last Saturday, we look back on ten of United’s latest, greatest strikes in the Premier League!
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Huntington’s disease is a genetic disorder caused by a breakdown of nerve cells in the brain. The disease affects an individual’s ability to move, their mood, and how they think. There’s currently no cure for Huntington’s disease, but there are types of gene therapy approaches that may offer hope for managing or slowing symptoms.
A New Tinnitus CURE? | OTO-313. Dr. Cliff Olson, Audiologist and founder of Applied Hearing Solutions in Phoenix Arizona, discusses a drug that is currently undergoing FDA clinical trials to see if it could be a CURE for Tinnitus.
Check out the NeuroTinnitus Brain Retraining Program: https://www.neurotinnitus.com/go?affiliate_id=2431398
American Tinnitus Association: https://ATA.org
Otonomy: https://Otonomy.com
OTO-313 Clinical Trials: https://clinicaltrials.gov/ct2/show/NCT03918109
A cure for tinnitus is something that has eluded researchers. With millions of individuals world wide suffering from this annoying condition that causes ringing in the ears, a cure is something that the world is in desperate need of. A pharmaceutical company Otonomy is trying to change that. They are searching for a cure for tinnitus and other ear related conditions. By using Gacyclidine a non-competitive NMDA receptor antagonist, is a Phencyclidine derivative with neuroprotective properties, they hope to reverse tinnitus or at least suppress it. Gacyclidine is closely related to another drug called Phencyclidine which is more commonly known as PCP, which is a hallucinogenic drug. Currently in Phase 1/2 of FDA clinical trials, they hope to show a positive impact of Gacyclidine on tinnitus. Results of their safety and efficacy trials should be published by the end of 2020.
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It’s been a road from hell but I got better and am improving a lot every day.
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Learn all about genetic disorders in just a few minutes! Jessica Pamment, professional lecturer at DePaul University, details the diseases that result from mutations in damaged genes or abnormal numbers of chromosomes.
This video is part of a complete Introduction to Biology series presented in short digestible summaries!
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What if humans could be edited to run faster, jump higher, and think bigger? What if disease could be eradicated before it ever came to be? These are the questions that no longer belong in just comic books, but in the laboratory of the Innovative Genomics Institute’s Scientific Director, Jacob Corn. In this talk, he explores the future and ethics of CRISPR/Cas-9 genome editing.
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Jacob Corn is the Managing Director and Scientific Director of the Innovative Genomics Initiative and faculty at UC Berkeley in the department of Molecular & Cell Biology. Jacob’s research generally bridges reductionist mechanism with cell biology, with the overarching goal of understanding how biophysical properties interact within the cellular environment to shape signaling behavior and how disease arises when these properties go awry. As the director of the IGI, Jacob is committed to pushing the boundaries of next-generation genome editing for transformative insights into fundamental biologies and to laying the groundwork for clinical and commercial applications of the technology.
This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at http://ted.com/tedx
To listen to more of David Weatherall’s stories, go to the playlist: https://www.youtube.com/playlist?list=PLVV0r6CmEsFxwQ7NSziz_XdC66gP3lyYj
British scientist David Weatherall (1933-2018) was a world renowned expert on blood diseases, in particular thalassemias, and used his expertise to help in developing countries. He founded the WIMM at Oxford in 1989 and was knighted in 1987. [Listener: Marcus Pembrey]
TRANSCRIPT: Just before I got- left Liverpool, I got a phone call from a technician from a hospital over on the Wirral, saying that, he’d had a blood from a child, a mentally retarded child, and seen some lumps in the red cells and could they be haemoglobin H. A bloomin’ good technician actually. So, I, so and he sent over a sample, and this was clearly mild haemoglobin H disease, and I went over and saw the family and the parents, and it didn’t look kind of quite right. The child- Inherited the pattern in the parents, and I, I didn’t know what to make of this, so like a lot of these things, I put it away in the drawer, and just after moving to Oxford I got a letter, again, out of the blue, from a Colonel Nicholas Bethlenfalvay from some military hospital in the Deep South of the States. He said he’s got a patient that he thought had haemoglobin H disease, and he was mentally retarded, could we help him sort it out. So, I remembered the Liverpool one, and then I saw a paper in some rather obscure haematological journal, which clearly had been rejected by most of the other journals, about a group in Scandinavia where they’d seen a patient with H disease and a mental retardation, and was just thrown into a group of patients with H disease. So I began to wonder, and so we worked up these, we got samples from the Scandinavian family, we worked up these families as best we could, and the mental retardation varied very widely, there were two of them were quite mild, one was quite severe and had dysmorphic features, and, but, and we did the biosynthesis and we obviously at that stage could, I think we could just, I’m not sure whether we were quite ready with Southern Blotting, I think we were, and we couldn’t find alpha thalassemia in some of the parents, that was the problem, oh, at least, not that we could identify at that stage. So I thought, well, should, you know, should we just sit on this, or should we write a paper, and I thought I will write a very cautious paper entitled Mental- ‘Haemoglobin H Disease Mental Retardation – A True Association or A Chance Association?’ And they, we sent it to the ‘New England Journal’, rather cheekily, and of course, Americans don’t like kind of, sexy titles, and they didn’t like the title at all, and they were going to reject it anyway, and I have to say that the paper would not have got published, except David Nathan, who’s on that editorial board, he thought there might be something, he told them they had to publish it, so they did. And of course, once something happens in a journal like that, you start to get sent patients, and they started to come in, and we had a series of very bright post-docs, Andrew Wilkie particularly, and Richard, and two or three others actually at the time, I think Richard came a little later, and they gradually started to take this apart. Andrew was particularly helpful phenotyping because he was, unlike me, a proper geneticist by then, and they did good genetic studies, and collected long series, and then did the genetics, and it became clear there were two types. There was one that was coded on the chromosome 16, usually due to deletions, and then the more interesting one, which was coded by the X chromosome. And then, much to their credit, they isolated the gene, and it’s been a very interesting story, hasn’t it? Indeed. So, but that again, it was just a kind of, having a look at something that doesn’t quite make sense at the beside, kind of approach, but I, I think that’s a good approach actually, sometimes, but anyway.
Huntington’s disease is a genetic, neurodegenerative disease with a devastating impact on individuals and entire families. Despite knowing the exact cause of Huntington’s disease since 1993, there still remains much unknown about this complex brain disease.
In this animation, Lauren Byrne, a Research Fellow at the UCL Huntington’s Disease Centre shares her personal experience with Huntington’s. She takes us inside the brain to explore the mechanism of this disease leading to the cognitive, behavioural and motor symptoms in Huntington’s.
This is a Roche video developed in collaboration with Ed Wild, also from UCL Huntington’s Disease Centre, George Yohrling from the Huntington’s Disease Society of America, and Roger and Brenda Wylie, a family living with Huntington’s disease.
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Do you know the meaning of words like Patola, Lakk and Kanjar? If not, watch this Punjabi dictionary with #AmmyVirk where teaches all the words from the world of popular Punjabi songs.
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